| Yazarlar (6) |
Veysel Çomaklı
Ağrı İbrahim Çeçen Üniversitesi, Türkiye |
|
Rüya Sağlamtaş
Türkiye |
Prof. Dr. Müslüm KUZU
Türkiye |
|
Yalçın Karagöz
Türkiye |
|
Tuba Aydın
Türkiye |
|
Ramazan Demirdağ
Türkiye |
| Özet |
| In the study, water, ethanol, methanol, dichloromethane, and acetone extracts of Asparagus officinalis L. were obtained by maceration. DPPH⋅, ABTS⋅ , FRAP, and CUPRAC methods determined the antioxidant capacities of all extracts. Moreover, the in vitro effects of extracts on acetylcholinesterase (AChE), butyrylcholinesterase (BChE), carbonic anhydrase (CA)-I, CA-II and α-Glycosidase were investigated. At a 10 μg/ml concentration, the extract with the highest Fe reduction capacity was ethanol (AE), and the extract with the highest Cu reduction capacity was acetone (AA). AE for AChE (IC =21.19 μg/ml) and α-Glycosidase (IC : 70.00 μg/ml), methanol (AM) for BChE (IC =17.33 μg/ml), CA-I and II (IC =79.65 and 36.09 μg/ml, respectively) showed the most potent inhibition effect. The content analysis of acetone extract was performed with LC/MS-MS, the first three phytochemicals found most were p-Coumaric acid, rutin, and 4-hydroxybenzoic acid (284.29±3.97, 135.39±8.19, and 102.06±5.51 μg analyte/g extract, respectively). |
| Anahtar Kelimeler |
| asparagus officinalis | carbonic anhydrase | cholinesterase | inhibition | α-glycosidase |
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale |
| Dergi Adı | CHEMISTRY & BIODIVERSITY |
| Dergi ISSN | 1612-1872 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q3 |
| Makale Dili | Türkçe |
| Basım Tarihi | 05-2023 |
| Cilt No | 20 |
| Sayı | 5 |
| Doi Numarası | 10.1002/cbdv.202201231 |
| Makale Linki | http://dx.doi.org/10.1002/cbdv.202201231 |
| Atıf Sayıları | |
| WoS | 4 |
| Google Scholar | 8 |
