Evaluation of Antibacterial and Biocompatibility of Radiopaque Bioactive Glass-Based Endodontic Cements
Yazarlar (5)
Prof. Dr. Erkan KOÇ
Karabük Üniversitesi, Türkiye
Doç. Dr. Olcay ÖZDEMİR
Karabük Üniversitesi, Türkiye
Türkiye
Türkiye
| Makale Türü | Özgün Makale |
| Makale Alt Türü | SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale |
| Dergi Adı | Ceramics International |
| Dergi ISSN | 0272-8842 Wos Dergi Scopus Dergi |
| Dergi Tarandığı Indeksler | SCI-Expanded |
| Dergi Grubu | Q1 |
| Makale Dili | İngilizce |
| Basım Tarihi | 01-2025 |
| Cilt No | 51 |
| Sayı | 10 |
| Sayfalar | 12645 / 12653 |
| DOI Numarası | 10.1016/j.ceramint.2025.01.104 |
| Özet |
| This study evaluated the antibacterial properties, hemocompatibility, cytotoxicity, and genotoxicity of bioactive glass ceramic-based endodontic cement formulated with various radiopaque active ingredients with varying concentrations (0, 15, and 20 wt.%). Antibacterial activity against E. faecalis was assessed using colony-forming unit (CFU) assays. The results showed significant antimicrobial activity of the bioactive glass-based cement, which was enhanced by adding radiopaque active ingredients. Lanthanum oxide exhibited the highest antibacterial activity at a concentration of 20%, reducing the CFU count from 6,000,000 (control) to 1,190,000. Bismuth oxide and samarium oxide also showed dose-dependent improvements in antibacterial properties. Hemocompatibility analysis revealed that all cement samples, including those containing radiopaque agents, remained nonhemolytic after 1-hour- and 24-hour … |
| Anahtar Kelimeler |
| Bioactive glass-based endodontic cement | Antibacterial properties | Hemocompatibility | Cytotoxicity | Genotoxicity |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| WoS | 6 |
| Google Scholar | 6 |