Potential Applications of Endo-beta-N-Acetylglucosaminidases From Bifidobacterium longum Subspecies infantis in Designing Value-Added, Next-Generation Infant Formulas
Yazarlar (7)
Arş. Gör. Hatice Duman Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Merve Kaplan Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Ayşenur Arslan Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Arif Sercan Şahutoğlu Çanakkale Onsekiz Mart Üniversitesi, Türkiye
Doç. Dr. Hacı Mehmet KAYILI Karabük Üniversitesi, Türkiye
Steven A. Frese University Of Nevada, Reno, Amerika Birleşik Devletleri
Sercan Karav Çanakkale Onsekiz Mart Üniversitesi, Türkiye
| Makale Türü |
Diğer (Teknik, not, yorum, vaka takdimi, editöre mektup, özet, kitap krıtiği,
araştırma notu, bilirkişi raporu ve benzeri)
(SCI, SSCI, AHCI, SCI-Exp dergilerinde yayınlanan teknik not,
editöre mektup, tartışma, vaka takdimi ve özet türünden makale)
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| Dergi Adı | Frontiers in Nutrition (Q1) | ||
| Dergi ISSN | 2296-861X Wos Dergi Scopus Dergi | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 04-2021 |
| Cilt / Sayı / Sayfa | 8 / 1 / 646275–0 | DOI | 10.3389/fnut.2021.646275 |
| Makale Linki | https://www.frontiersin.org/articles/10.3389/fnut.2021.646275/full | ||
| UAK Araştırma Alanları |
Analitik Kimya
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| Özet |
| Human milk is the optimal source of infant nutrition. Among many other health benefits, human milk can stimulate the development of a Bifidobacterium-rich microbiome through human milk oligosaccharides (HMOs). In recent years, the development of novel formulas has placed particular focus on incorporating some of the beneficial functional properties of human milk. These include adding specific glycans aimed to selectively stimulate the growth of Bifidobacterium. However, the bifidogenicity of human milk remains unparalleled. Dietary N-glycans are carbohydrate structures conjugated to a wide variety of glycoproteins. These glycans have a remarkable structural similarity to HMOs and, when released, show a strong bifidogenic effect. This review discusses the biocatalytic potential of the endo-β-N-acetylglucosaminidase enzyme (EndoBI-1) from Bifidobacterium longum subspecies infantis (B. infantis), in releasing N-glycans inherently present in infant formula as means to increase the bifidogenicity of infant formula. Finally, the potential implications for protein deglycosylation with EndoBI-1 in the development of value added, next-generation formulas are discussed from a technical perspective. |
| Anahtar Kelimeler |
| bifidobacteria | endo-β-N-acetylglucosaminidase | human milk oligosaccharides | infant formula | N-glycans |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 30 |
| Scopus | 30 |
| Google Scholar | 36 |