A novel method to identify and grade DNA damage on comet images
 
Yazarlar (2)
Doç. Dr. Muhammed Kamil TURAN Karabük Üniversitesi, Türkiye
Doç. Dr. Eftal ŞEHİRLİ Karabük Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Computer Methods and Programs in Biomedicine (Q2)
Dergi ISSN 0169-2607
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce Basım Tarihi 08-2017
Kabul Tarihi Yayınlanma Tarihi 01-08-2017
Cilt / Sayı / Sayfa 147 / 1 / 19–27 DOI 10.1016/j.cmpb.2017.06.002
Makale Linki http://dx.doi.org/10.1016/j.cmpb.2017.06.002
UAK Araştırma Alanları
Makine Öğrenmesi
Özet
Background and objectiveIn recent years, development of software programs in medicine field has proceeded in a rapid manner. Comet assay is one of the research methods in medicine field that displays whether DNA has damage. In this study, it is aimed to share experience of dynamic time warping method and decision tree to decide whether DNA has damage and grade DNA damage by means of the software program.MethodsThe application analyzes manually extracted RGB single comet images whose centers are manually marked. The application performs pixel profile analysis at the directions of vertical and horizontal based on the center of comet. The bidirectional pixel profile results are used as inputs of dynamic time warping. Four novel and one conventional measurement parameters some of which are calculated by dynamic time warping are given to decision tree.ResultsThe decision tree identifies …
Anahtar Kelimeler
Comet | Decision tree | DNA damage | Dynamic time warping | Image processing
Science Direct
BM Sürdürülebilir Kalkınma Amaçları
Atıf Sayıları
Web of Science 13
Scopus 16
Google Scholar 20
A novel method to identify and grade DNA damage on comet images

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