Identification of column edges of DNA fragments by using K-means clustering and mean algorithm on lane histograms of DNA agarose gel electrophoresis images
Yazarlar (4)
Doç. Dr. Muhammed Kamil TURAN Karabük Üniversitesi, Türkiye
Doç. Dr. Eftal ŞEHİRLİ Karabük Üniversitesi, Türkiye
Abdullah Elen Karabük Üniversitesi, Türkiye
Prof. Dr. İsmail Rakıp KARAŞ Karabük Üniversitesi, Türkiye
Bildiri Türü Tebliğ/Bildiri Bildiri Dili İngilizce
Bildiri Alt Türü Tam Metin Olarak Yayınlanan Tebliğ (Uluslararası Kongre/Sempozyum)
Bildiri Niteliği Web of Science Kapsamındaki Kongre/Sempozyum
DOI Numarası 10.1117/12.2197221
Kongre Adı Seventh International Conference on Digital Image Processing (ICDIP 2015)
Kongre Tarihi 09-04-2015 / 10-04-2015
Basıldığı Ülke Amerika Birleşik Devletleri Basıldığı Şehir Los Angeles
Bildiri Linki http://dx.doi.org/10.1117/12.2197221
UAK Araştırma Alanları
Makine Öğrenmesi
Özet
Gel electrophoresis (GE) is one of the most used method to separate DNA, RNA, protein molecules according to size, weight and quantity parameters in many areas such as genetics, molecular biology, biochemistry, microbiology. The main way to separate each molecule is to find borders of each molecule fragment. This paper presents a software application that show columns edges of DNA fragments in 3 steps. In the first step the application obtains lane histograms of agarose gel electrophoresis images by doing projection based on x-axis. In the second step, it utilizes k-means clustering algorithm to classify point values of lane histogram such as left side values, right side values and undesired values. In the third step, column edges of DNA fragments is shown by using mean algorithm and mathematical processes to separate DNA fragments from the background in a fully automated way. In addition to this, the …
Anahtar Kelimeler
DNA fragments | K-means clustering algorithm | Lane histogram | Mean algorithm