Assessing Microstructural, Biomechanical, and Biocompatible Properties of TiNb Alloys for Potential Use as Load-Bearing Implants
Yazarlar (9)
Yan Huang
Yüksel Çetin
Türkiye
Türkiye
Doç. Dr. Alper İNCESU Karabük Üniversitesi, Türkiye
Doç. Dr. Hüseyin DEMİRTAŞ Karabük Üniversitesi, Türkiye
Mehmet Kaya Türkiye
Yasemin Yıldızhan
Türkiye
Türkiye
Merve Tosun Türkiye
Gülşah Akbaş
| Makale Türü | Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale) | ||
| Dergi Adı | JOURNAL OF FUNCTIONAL BIOMATERIALS (Q1) | ||
| Dergi ISSN | 2079-4983 Dergi Bilgileri (2024) | ||
| Dergi Tarandığı Indeksler | SCI-Expanded | ||
| Makale Dili | Türkçe | Basım Tarihi | 09-2024 |
| Cilt / Sayı / Sayfa | 15 / 9 / 1–17 | DOI | 10.3390/jfb15090253 |
| Makale Linki | http://dx.doi.org/10.3390/jfb15090253 | ||
| UAK Araştırma Alanları |
Biyomalzemeler
Metalik Malzemeler
|
||
| Özet |
| Titanium-Niobium (TiNb) alloys are commonly employed in a number of implantable devices, yet concerns exist regarding their use in implantology owing to the biomechanical mismatch between the implant and the host tissue. Therefore, to balance the mechanical performance of the load-bearing implant with bone, TiNb alloys with differing porosities were fabricated by powder metallurgy combined with spacer material. Microstructures and phase constituents were characterized with energy dispersive spectroscopy (EDS), scanning electron microscopy (SEM), and X-ray diffraction (XRD). The mechanical properties were tested by uniaxial compression, and the corrosion performance was determined via a potentiodynamic polarization experiment. To evaluate a highly matched potential implant with the host, biocompatibilities such as cell viability and proliferation rate, fibronectin adsorption, plasmid-DNA interaction, and an SEM micrograph showing the cell morphology were examined in detail. The results showed that the alloys displayed open and closed pores with a uniform pore size and distribution, which allowed for cell adherence and other cellular activities. The alloys with low porosity displayed compressive strength between 618 MPa and 1295 MPa, while the alloys with high porosity showed significantly lower strength, ranging from 48 MPa to 331 MPa. The biological evaluation of the alloys demonstrated good cell attachment and proliferation rates. |
| Anahtar Kelimeler |
| powder metallurgy | spacer material | load-bearing implant | corrosion performance | cytocompatibility |
BM Sürdürülebilir Kalkınma Amaçları
| Atıf Sayıları | |
| Web of Science | 6 |
| Google Scholar | 10 |