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A randomized automated thresholding method to identify comet objects on comet assay images       
Yazarlar (3)
Doç. Dr. Eftal ŞEHİRLİ Doç. Dr. Eftal ŞEHİRLİ
Karabük Üniversitesi, Türkiye
Doç. Dr. Muhammed Kamil TURAN Doç. Dr. Muhammed Kamil TURAN
Karabük Üniversitesi, Türkiye
Dr. Öğr. Üyesi Emrullah DEMİRAL Dr. Öğr. Üyesi Emrullah DEMİRAL
Karabük Üniversitesi, Türkiye
Devamını Göster
Özet
Deoxyribonucleic acid (DNA) is an important molecule which has a tendency to easily have damage. Etiology of many diseases like cancer, cardiovascular disease, and immune deficiency is asserted to be based on DNA damage. Comet assay is a reliable, cheap and easy method to specify whether DNA has damage or not. The fact that the number of developing software applications on demand increases day by day comes into prominence of obtaining quick and accurate results in medicine field. In this study, a software application is developed which single comet objects on comet assay images are identified to perform analysis, calculation of comet parameters and decision regarding whether DNA has damage or not. Comet images are converted to red channel images, the randomized automated thresholding method is applied on red channel images and connected component labeling obtains each single comet object. This paper mainly focuses on specifications and mathematical model of the thresholding method.
Anahtar Kelimeler
Comet | DNA damage | Image processing | Randomized thresholding method
Bildiri Türü Tebliğ/Bildiri
Bildiri Alt Türü Tam Metin Olarak Yayımlanan Tebliğ (Uluslararası Kongre/Sempozyum)
Bildiri Niteliği Web of Science Kapsamındaki Kongre/Sempozyum
Bildiri Dili İngilizce
Kongre Adı ICCIP 2017: 2017 the 3rd International Conference on Communication and Information Processing
Kongre Tarihi 24-11-2017 / 26-11-2017
Basıldığı Ülke Japonya
Basıldığı Şehir Tokyo