Investigation of the Protective Effects of Synbiotic Buffalo Kefir in Rats With Type 1 Diabetes Mellitus
 
Yazarlar (6)
Dr. Öğr. Üyesi İlkay BURAN Karabük Üniversitesi, Türkiye
Arş. Gör. Şeyda SEÇGİN Karabük Üniversitesi, Türkiye
H. Ceren Akal
Ankara Üniversitesi, Türkiye
Arş. Gör. Oguzhan Koca Karabük University Training And Research Hospital, Türkiye
Mehmet Ozdemir Karabük Üniversitesi, Türkiye
Prof. Dr. Tahir KAHRAMAN Karabük Üniversitesi, Türkiye
Makale Türü Özgün Makale (SSCI, AHCI, SCI, SCI-Exp dergilerinde yayınlanan tam makale)
Dergi Adı Molecular Nutrition and Food Research (Q1)
Dergi ISSN 1613-4125 Dergi Bilgileri (2025)
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili Türkçe Basım Tarihi 11-2025
Cilt / Sayı / Sayfa 69 / 24 / – DOI 10.1002/mnfr.70324
Makale Linki https://doi.org/10.1002/mnfr.70324
UAK Araştırma Alanları
Gıda Mikrobiyolojisi Süt ve Süt Ürünleri Teknolojisi Fonksiyonel Gıdalar
Özet
The aim of this study is to determine the effects of synbiotic buffalo kefirs on streptozotocin (STZ)‐induced in vivo type 1 diabetes mellitus markers. Kefir was produced by adding Lactobacillus acidophilus, Bifidobacterium bifidum, and fructooligosaccharide (FOS) to buffalo milk using DVS kefir culture. For the in vivo study, 70 male rats were fed buffalo kefir samples for 28 days. Physicochemical (pH, titration acidity, dry matter, fat, protein) and microbiological analyses were performed on kefir samples. Blood samples from the experimental animals were analyzed for malondialdehyde (MDA), superoxide dismutases (SOD), glutathione peroxidase (GPX), and diabetes parameters. The results showed that the probiotic bacterial count was highest in the sample containing FOS+Lb. acidophilus. In diabetic rats, triglyceride levels decreased significantly in the group consuming the FOS+B. bifidum sample. High‐density …
Anahtar Kelimeler
buffalo milk | functional food | in vivo experiment | streptozotocin | synbiotic kefir | type 1 diabetes mellitus
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Investigation of the Protective Effects of Synbiotic Buffalo Kefir in Rats With Type 1 Diabetes Mellitus

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