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In vitro antimicrobial susceptibility of Brucella melitensis isolates from sheep in an area endemic for human Brucellosis in Turkey     
Yazarlar (3)
Ziya İlhan
Yüzüncü Yıl Üniversitesi, Türkiye
Prof. Dr. Hasan SOLMAZ Prof. Dr. Hasan SOLMAZ
Adıyaman Üniversitesi, Türkiye
İsmail Hakkı Ekin
Yüzüncü Yıl Üniversitesi, Türkiye
Devamını Göster
Özet
The aim of this study was to assess in vitro antimicrobial susceptibility of Brucella melitensis isolates isolated from naturally infected sheep cases in an area where human brucellosis is endemic, focusing on rifampin (RIF), streptomycin (SM), ciprofloxacin (CPFX), trimethoprim/sulfamethoxazole (TMP/SMZ), gentamicin (GM) and tetracycline (TC) and on 11 other antimicrobials. The identification and typing of Brucella isolates were carried out using standard classification tests and polymerase chain reaction (PCR) methods. Antimicrobial susceptibility testing was carried out on Mueller-Hilton agar. The resistance to SM, CPFX and GM was determined at the rate of 7.3% and to RIF at the rate of 9.7%. The highest (46.3%) resistance was determined against TMP/SMZ. All strains were found to be sensitive to TC at the rate of 100.0%. In conclusion, ovine origin B. melitensis strains evaluated in this study were resistant to at least one antimicrobial (51.2%) that is commonly used in human clinical medicine against brucellosis.
Anahtar Kelimeler
antimicrobial susceptibility | Brucella melitensis | sheep | zoonosis
Makale Türü Özgün Makale
Makale Alt Türü SSCI, AHCI, SCI, SCI-Exp dergilerinde yayımlanan tam makale
Dergi Adı J. Vet. Med. Sci.
Dergi ISSN 0916-7250 Wos Dergi Scopus Dergi
Dergi Tarandığı Indeksler SCI-Expanded
Makale Dili İngilizce
Basım Tarihi 08-2013
Cilt No 75
Sayı 8
Sayfalar 1035 / 1040
Doi Numarası 10.1292/jvms.12-0163
Makale Linki https://www.jstage.jst.go.jp/article/jvms/75/8/75_12-0163/_pdf